Estimation of Ferrioxamine and Desferrioxamine in Urine.
نویسندگان
چکیده
A method is described for the estimation of ferrioxamine and of desferrioxamine when either or both are present in urine.
منابع مشابه
Estimation of ferrioxamine in jaundiced urine.
A simple modification to Fielding and Brunström's method for the estimation of ferri-oxamine is described for use with jaundiced urine. Manufactured ferrioxamine HC1 may be slightly impure, and when used for standard purposes should be rendered anhydrous and checked for iron content. Standard ferrioxamine solutions suitable for calibrating Fielding and Brunström's method may be prepared by addi...
متن کاملDesferrioxamine chelatable body iron.
Further experience with the differential ferrioxamine test (Fielding, 1965) for the measurement of body-iron chelation has led to modifications which include (1) an improved standard for the estimation of ferrioxamine, (2) simplified preparation of the test dose, (3) restriction of fluid during the test and (4) simplified methods of calculation. The principle of the test remains the same: an in...
متن کاملChelation of transferrin iron by desferrioxamine in K562 cells. The partition of iron between ferrioxamine and ferritin.
In this study we have determined whether desferrioxamine can chelate iron delivered to human leukaemic cells by the transferrin endocytic cycle. The cellular uptake of desferrioxamine was investigated by an indirect method in which the conversion of repeated pulses of [59Fe]transferrin to [59Fe]ferrioxamine was determined at two concentrations of the drug. Maximum generation of [59Fe]ferrioxami...
متن کاملchelatable body iron
SYNOPSIs The differential ferrioxamine test is a simple method for the measurement of chelation of body iron by desferrioxamine. A single six-hour specimen of urine is obtained after intravenous Desferal, accompanied by 59Fe-ferrioxamine. Two values are measured: Fd, the excretion of ferrioxamine derived from body iron by chelation, and Fex, the proportion of ferrioxamine excreted from a known ...
متن کاملIron chelation with desferrioxamine B in adults with asymptomatic Plasmodium falciparum parasitemia.
To determine if iron chelation therapy has activity against human malaria, we administered desferrioxamine B in amounts of 100 mg/kg per day by continuous 72-hour subcutaneous infusions to 28 volunteers with asymptomatic Plasmodium falciparum infection in a randomized, double-blind, placebo-controlled crossover trial. Peripheral blood concentrations of P falciparum ring forms were determined at...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of clinical pathology
دوره 17 شماره
صفحات -
تاریخ انتشار 1964